2 Million Dogs Foundation Presents $50,000 Donation to Princeton

The 2 Million Dogs Foundation presented a check for $50,000 to Princeton University on Wednesday, January 11, to help fund the school’s Molecular Study of Canine Mammary Tumor Development and Progression: from Genome To Clinical Outcome.
The 2 Million Dogs Foundation is committed to discovering the common links between canine and human cancers and the causes of these cancers through comparative oncology research.
The money presented was raised by holding a series of walks, called “The Puppy Up! Walk.” The events served not only as a fundraiser, but also brought attention to the field of comparative oncology, which is relatively new. 2 Million Dogs hopes to educate people about its tremendous potential through a global campaign of strategic partnerships, seminars, speaking engagements, social media, events, broadcasts, and other forms of media.
“Through The Puppy Up! Walk, we are building the largest pet and people cancer community in the world; from business people to artists to scientists and humanitarians, a partnership forged with the singular purpose of ridding the world of its deadliest disease,” said Luke Robinson the organization’s Founder.
The organization’s scientific objectives are: Broadening our understanding of the links between human and companion animal cancer, creating a cross institutional collaborative platform, developing new approaches to research, and funding translational cancer studies that benefit both pets and people.
Mammary tumors are the most common tumors in intact female dogs, and in humans, breast cancer is the most commonly diagnosed cancer in women – approximately one in eight women develop breast cancer during their lifetime. Mammary tumors in dogs and breast cancer in women have many similarities, both in terms of risk factors and biology.
An important challenge in fighting breast cancer is understanding the malignant progression of tumors. 2 Million Dogs foundation is funding a genome-wide study of the molecular alterations associated with this progression based on canine mammary tumors at different stages of transformation.
In order to be able to do this research, Dr. Karin Sorenmo of the University of Pennsylvania has established a Shelter Canine Mammary Tumor Program. This research is a combination of her clinical expertise and Dr. Troyanskaya’s group (Princeton University) expertise in cancer genomics and bioinformatics.
Robinson says “Collaborating with Princeton University and the University of Pennsylvania is an intersection of great ideas and great expectations and we feel the research will provide us with invaluable insight into the most prolific cancer afflicting women in the United States.”
This Program thus forms a true bridge between clinical and translational research, integrating clinical care with cutting-edge biomedical science while providing homeless dogs with the high quality treatment they need to survive. By providing this care they are able to utilize their clinical information and tumor tissue for research purposes, thus providing care; advancing research. This research is to our knowledge the first genome-wide molecular study of natural tumor progression



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